The remaining 75% is nitrofurantoin monohydrate contained in a powder blend which, upon exposure to gastric and intestinal fluids, forms a gel matrix that releases nitrofurantoin over time. Twenty-five percent is macrocrystalline nitrofurantoin, which has slower dissolution and absorption than nitrofurantoin monohydrate. 40, gelatin, lactose, magnesium stearate, povidone, talc, and titanium dioxide.įDA approved dissolution method differs from the current USP monograph dissolution methods.Įach nitrofurantoin monohydrate/macrocrystals capsule contains two forms of nitrofurantoin. Inactive Ingredients: Each capsule contains carbomer 934P, corn starch, compressible sugar, D&C Yellow No. The chemical name of nitrofurantoin monohydrate is 1-methylene] amino]-2,4- imidazolidinedione monohydrate. The chemical name of nitrofurantoin macrocrystals is 1-methylene] amino]-2,4-imidazolidinedione. The nitrofurantoin monohydrate/macrocrystals capsules brand of nitrofurantoin is a hard gelatin capsule shell containing the equivalent of 100 mg of nitrofurantoin in the form of 25 mg of nitrofurantoin macrocrystals and 75 mg of nitrofurantoin monohydrate. Nitrofurantoin is an antibacterial agent specific for urinary tract infections. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.Ĭopyright 1996-2018 Cerner Multum, Inc.
The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drug information contained herein may be time sensitive. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. You may report side effects to FDA at 1-80.Įvery effort has been made to ensure that the information provided by Cerner Multum, Inc. Call your doctor for medical advice about side effects. This is not a complete list of side effects and others may occur. Serious side effects may be more likely in older adults and those who are ill or debilitated.
numbness, tingling, or pain in your hands or feet.fever, chills, body aches, tiredness, unexplained weight loss.new or worsening cough, trouble breathing.sudden chest pain or discomfort, wheezing, dry cough or hack.